USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P08779 USC-OGP 2-DE database:  P08779 P08779 General information about the entry View entry in simple text format Entry name K1C16_HUMAN Primary accession number P08779 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Keratin, type I cytoskeletal 16; AltName: Full=Cytokeratin-16; Short=CK-16; AltName: Full=Keratin-16; Short=K16;. Gene name Name=KRT16 Synonyms=KRT16A Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1192: pI=5.85; Mw=41038 SPOT OGP-1201: pI=5.96; Mw=39564 Cross-references UniProtKB/Swiss-Prot P08779; K1C16_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name K1C16_HUMAN Primary accession number P08779 Secondary accession number(s) A8K488 P30654 Q16402 Q9UBG8 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 177) Name and origin of the protein Description RecName: Full=Keratin, type I cytoskeletal 16; AltName: Full=Cytokeratin-16; Short=CK-16; AltName: Full=Keratin-16; Short=K16; Gene name Name=KRT16 Synonyms=KRT16A Encoded on Name=KRT16; Synonyms=KRT16A Keywords Coiled coil; Complete proteome; Direct protein sequencing; Disease mutation; Ectodermal dysplasia; Intermediate filament; Keratin; Methylation; Palmoplantar keratoderma; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M28439; AAA59460.1; -; Genomic_DNA EMBL M28432; AAA59460.1; JOINED; Genomic_DNA EMBL M28433; AAA59460.1; JOINED; Genomic_DNA EMBL M28434; AAA59460.1; JOINED; Genomic_DNA EMBL M28435; AAA59460.1; JOINED; Genomic_DNA EMBL M28436; AAA59460.1; JOINED; Genomic_DNA EMBL M28437; AAA59460.1; JOINED; Genomic_DNA EMBL M28438; AAA59460.1; JOINED; Genomic_DNA EMBL S79867; AAB35421.1; -; mRNA EMBL AF061809; AAD15829.1; -; Genomic_DNA EMBL AF061812; AAC99326.1; -; mRNA EMBL AK290853; BAF83542.1; -; mRNA EMBL CH471152; EAW60749.1; -; Genomic_DNA EMBL BC039169; AAH39169.1; -; mRNA EMBL S78514; AAB34564.1; -; Genomic_DNA CCDS CCDS11401.1; -; . PIR A33652; A33652; . PIR JC4313; JC4313; . RefSeq NP_005548.2; NM_005557.3; . UniGene Hs.655160; -; . ProteinModelPortal P08779; -; . SMR P08779; -; . BioGrid 110066; 36; . IntAct P08779; 68; . MINT MINT-1145021; -; . STRING 9606.ENSP00000301653; -; . iPTMnet P08779; -; . PhosphoSitePlus P08779; -; . SwissPalm P08779; -; . BioMuta KRT16; -; . DMDM 23503075; -; . PaxDb P08779; -; . PeptideAtlas P08779; -; . PRIDE P08779; -; . DNASU 3868; -; . Ensembl ENST00000301653; ENSP00000301653; ENSG00000186832; . GeneID 3868; -; . KEGG hsa:3868; -; . UCSC uc002hxg.5; human; . CTD 3868; -; . DisGeNET 3868; -; . GeneCards KRT16; -; . GeneReviews KRT16; -; . H-InvDB HIX0059709; -; . H-InvDB HIX0136649; -; . H-InvDB HIX0173645; -; . HGNC HGNC:6423; KRT16; . HPA CAB000136; -; . HPA HPA000539; -; . MalaCards KRT16; -; . MIM 144200; phenotype; . MIM 148067; gene; . MIM 167200; phenotype; . MIM 613000; phenotype; . neXtProt NX_P08779; -; . OpenTargets ENSG00000186832; -; . Orphanet 2199; Epidermolytic palmoplantar keratoderma; . Orphanet 2309; Pachyonychia congenita; . PharmGKB PA30210; -; . eggNOG ENOG410IFTF; Eukaryota; . eggNOG ENOG410Y9IV; LUCA; . GeneTree ENSGT00760000118808; -; . HOGENOM HOG000230975; -; . HOVERGEN HBG013015; -; . InParanoid P08779; -; . KO K07604; -; . OMA GHQTRPI; -; . OrthoDB EOG091G087I; -; . PhylomeDB P08779; -; . TreeFam TF332742; -; . Reactome R-HSA-6805567; Keratinization; . Reactome R-HSA-6809371; Formation of the cornified envelope; . GeneWiki Keratin_16; -; . GenomeRNAi 3868; -; . PRO PR:P08779; -; . Proteomes UP000005640; Chromosome 17; . Bgee ENSG00000186832; -; . CleanEx HS_KRT16; -; . ExpressionAtlas P08779; baseline and differential; . Genevisible P08779; HS; . GO GO:0005856; C:cytoskeleton; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005882; C:intermediate filament; NAS:UniProtKB; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB; . GO GO:0007568; P:aging; IDA:UniProtKB; . GO GO:0008283; P:cell proliferation; TAS:ProtInc; . GO GO:0070268; P:cornification; TAS:Reactome; . GO GO:0007010; P:cytoskeleton organization; NAS:UniProtKB; . GO GO:0008544; P:epidermis development; TAS:ProtInc; . GO GO:0061436; P:establishment of skin barrier; ISS:UniProtKB; . GO GO:0042633; P:hair cycle; IDA:UniProtKB; . GO GO:0006954; P:inflammatory response; ISS:UniProtKB; . GO GO:0045087; P:innate immune response; ISS:UniProtKB; . GO GO:0045104; P:intermediate filament cytoskeleton organization; IEA:Ensembl; . GO GO:0031424; P:keratinization; ISS:UniProtKB; . GO GO:0030216; P:keratinocyte differentiation; ISS:UniProtKB; . GO GO:0051546; P:keratinocyte migration; ISS:UniProtKB; . GO GO:0002009; P:morphogenesis of an epithelium; ISS:UniProtKB; . GO GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB; . InterPro IPR001664; IF; . InterPro IPR018039; Intermediate_filament_CS; . InterPro IPR002957; Keratin_I; . PANTHER PTHR23239; PTHR23239; 1; . Pfam PF00038; Filament; 1; . PRINTS PR01248; TYPE1KERATIN; . SMART SM01391; Filament; 1; . PROSITE PS00226; IF; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]